منابع مشابه
Diffuse low-grade gliomas
Description : Diffuse low-grade gliomas (WHO grade II) are a sub-group of rare and heterogeneous primary brain tumors that usually occur in young patients living a normal life until the onset of a first seizure. A good understanding of the natural history of these gliomas namely: their steady progression, infiltration along white matter fibers and especially the risk of malignant transformation...
متن کاملTemozolomide for low-grade gliomas
CME ABSTRACT Objective:To evaluate the predictive impact of chromosome 1p/19q deletions on the response and outcome of progressive low-grade gliomas (LGG) treated with up-front temozolomide (TMZ) chemotherapy. Methods: Adult patients with measurable, progressive LGG (WHO grade II) treated with TMZ delivered at the conventional schedule (200 mg/m/day for 5 consecutive days, repeated every 28 day...
متن کاملSecond Surgery in Insular Low-Grade Gliomas
BACKGROUND Given the technical difficulties, a limited number of works have been published on insular gliomas surgery and risk factors for tumor recurrence (TR) are poorly documented. OBJECTIVE The aim of the study was to determine TR in adult patients with initial diagnosis of insular Low-Grade Gliomas (LGGs) that subsequently underwent second surgery. METHODS A consecutive series of 53 pa...
متن کاملCurrent treatment of low grade gliomas
Low grade gliomas affect predominantly young adults, and have a relatively favorable prognosis compared to grade III and grade IV gliomas. The challenge for an optimal management of these patients is to find the balance between an optimal survival and the preservation of neurological function including cognition. Because all medical treatments may induce side effects, in young and nearly asympt...
متن کاملManagement of patients with low-grade gliomas.
The accurate diagnosis and management of patients who have infiltrating low-grade gliomas is increasing in importance. Recent advances in molecular characterization, imaging, and treatment of these tumors underscore this current focus of investigations.
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ژورنال
عنوان ژورنال: Neurosurgical Focus
سال: 2002
ISSN: 1092-0684
DOI: 10.3171/foc.2002.12.2.1